CD47-amyloid-β-CD74 signaling is a key driver of adaptive immunosuppression in sepsis, suppressing B cells and impairing ...

These receptors initiate two arms of the immune response — the innate and adaptive responses — that work together to fight infection in mammals. The innate response provides immediate protection.

The innate immune system acts quickly and non-specifically to detect and fight infections; the slower, adaptive immune response recognizes and targets specific pathogens. “Classically, what ...