This reduces bile acid production, causing harmful cholesterol byproducts to build up and form fatty deposits (xanthomas) in the brain, liver, skin, and tendons. Over time, it can cause nerve ...

New research reveals that specialized gut bacteria convert bile acids into powerful healing compounds, offering hope for ...

The disorder is characterized by reduced bile acid production in the liver, which leads to abnormal breakdown of cholesterol. The disease results in atypical cholesterol metabolites being ...

The human gut is home to trillions of bacteria that play vital roles in digestion, immunity, and overall health. When this ...

"They do all this by binding to FXR, which acts like a traffic light, controlling cholesterol metabolism and bile acid production to avoid excess buildup." Now the cross-campus collaboration ...

Study findings indicate therapeutic potential of microbiome-based intervention to restore bile acid balance and promote gut ...

A research team from the Medical University of Vienna has made further progress in the treatment of intestinal inflammation.

In primary human pulmonary arterial ECs, NCOA7 deficiency resulted in lysosomal dysfunction, lipid accumulation and production of proinflammatory oxysterols and bile acids that drove EC ...