Hepatic synthesis of bile acids is the primary pathway for cholesterol catabolism. The cholesterol 7α-hydroxylase enzyme (encoded by CYP7A1) represents the rate-limiting step of the multi ...

and conclude that postprandial bile-acid levels should be sufficient to trigger cyclic AMP production and increase D2 activity. These findings further the understanding of energy homeostasis ...

"They do all this by binding to FXR, which acts like a traffic light, controlling cholesterol metabolism and bile acid ...

The research teams led by Kristina Schoonjans and Rizlan Bernier-Latmani at EPFL, have identified Clostridium scindens, a bacterium that converts primary bile acids into 7α-dehydroxylated bile ...

A new study from the Air Force Medical University, China shows that Sevoflurane (Sev) influences social functioning via the ...

One of the hallmarks of UC is a deficiency in certain bile acids, molecules that help digest fats and regulate gut health. These molecules aren't just produced by the liver—they are further ...

A study shows that the semi-synthetic bile acid NorUDCA inhibits in the intestine the formation of pro-inflammatory T helper 17 cells (TH17) and at the same time promotes the generation of anti ...