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Unlike unfractionated heparin (UFH), the low-molecular-weight heparin enoxaparin (Lovenox) is excreted mainly by the kidneys.
Enoxaparin [23] Observe patients with moderate (CL cr of 30-50 mL/min) or mild (CL cr of 50-80 mL/min) renal impairment carefully for signs and symptoms of bleeding. Use with caution in elderly ...
Patients with moderate renal impairment are at increased risk of major bleeding resulting from enoxaparin treatment compared with patients who have normal kidney function, a study found.
Such substance specific studies in renal failure have been published for enoxaparin for a long time and have resulted in different dosage recommendations (1, 2, product information).
Hulot JS et al. (2005) Dosing strategy in patients with renal failure receiving enoxaparin for the treatment of non-ST-segment elevation acute coronary syndrome.
Enoxaparin Medication Information Learn everything you need to know about Enoxaparin-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.
For patients with chronic kidney disease who undergo total hip replacement, the rate of major venous thromboembolism is significantly higher in those treated with enoxaparin compared to those ...
The efficacy and safety of prolonging prophylaxis for venous thromboembolism in medically ill patients beyond hospital discharge remain uncertain. We hypothesized that extended prophylaxis with api ...
Fondaparinux may be safer than enoxaparin as treatment for non-ST-segment elevation ACS in patients with renal dysfunction.
Despite its limitations, unfractionated heparin has been the standard anticoagulant used during percutaneous coronary intervention (PCI). Several small studies have suggested that intravenous enoxa ...
Pope Francis remained in critical condition Sunday and blood tests show early kidney failure but he remains alert and “well-oriented,” and attended Mass, the Vatican said, as the 88-year-old ...