A global research collaboration has revealed how certain gut cells switch on pain signals, which can linger long after the ...
Circulating serotonin is produced in the duodenum by enterochromaffin cells, specialized endocrine cells in the epithelia lining the gut, and functions within a specialized neuroendocrine network.
Enterochromaffin (EC) cells and expression of leptin, PAX4 (critical factor for EC specification), tryptophane hydroxylase-1 (TPH1, the peripheral rate-limiting enzyme for 5HT) and 5HT were ...