A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a ...

CDX2 binds distinct targets in developing and adult intestinal epithelial cells based on the distribution of its motifs with and without CpG. Here, the authors show that loss of DNA methylation ...

A team of researchers has developed a "gut-on-chip" (a miniature model of the human intestine on a chip-sized device) capable ...

Inflammatory bowel diseases (IBDs), which include ulcerative colitis (UC) and Crohn’s disease (CD), are chronic conditions ...

ECMO was associated with increased fas ligand expression in intestinal mast cells, which was induced through activation of the p38 mitogen-activated protein kinase. We conclude that epithelial ...

Iris Kulbatski, a neuroscientist by training and word surgeon by trade, is a science editor with The Scientist's Creative Services Team. She holds a PhD in Medical Science and a Certificate in ...

2 Different scaffolds allow researchers to finetune their monolayer systems and investigate unique properties of the human intestinal tract. Monolayer systems cultured on porous membranes replicate ...

Pathogen-fighting immune cells called tissue-resident memory CD8 T cells (TRM cells) go through a surprising transformation -- and relocation -- as they fight infections in the small intestine.