A recent study published in eGastroenterology introduces young rabbits with CF as a novel and accessible model to study CF-related pancreatic endocrine pathology. This model offers an ...

An innovative organoid model mirrors the pancreas' complexity, generating all three key cell types to explore development and possible regeneration. Laura is an assistant editor for The Scientist. She ...

Adding immunotherapy to new KRAS inhibitors boosted responses in preclinical models, setting the stage for future trials of the combination strategy.

A team of German scientists and biotech company Dynamic42 have jointly developed a ‘tumour-on-chip’ model of pancreatic ...

Adding immunotherapy to a new type of inhibitor that targets multiple forms of the cancer-causing gene mutation KRAS kept ...

Pancreatic cancer remains one of the most challenging tumors to treat, partly because it is often discovered at advanced ...

Cell line-specific efficacy profiles: SIL204 showed robust activity across multiple pancreatic cancer cell lines with ...

Mar. 10, 2025 — A new study suggests that chronic stress and an unhealthy diet may work together to fuel the early development of pancreatic cancer, shedding light on how lifestyle factors ...

When the researchers blocked the neural connection to the pancreatic tumor in a mouse model using a targeted neurotoxin, the tumor became sensitive to the checkpoint inhibitor nivolumab again and ...

Pancreatic cancer is generally characterized by a poor prognosis. In a model of pancreatic ductal adenocarcinoma, extrachromosomal DNAs are shown to be a source of high-level focal amplification ...