Spironolactone – sometimes called “spiro” for short – has been a miracle drug for many suffering from acne, PCOS, and hair loss. Typically taken orally or in combination with other topical ...

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Italian biotech Cassiopea has won US approval for Winlevi, a topical therapy it says is the first new approach to treating acne in nearly 40 years. An androgen receptor inhibitor, Winlevi ...

The landmark Randomized Aldactone Evaluation Study (RALES), published in 1999, showed that spironolactone, a potassium-sparing diuretic, improves outcomes in patients with severe heart failure.

Drugs that interfere with the renin–angiotensin system can provide renoprotection in patients with diabetic nephropathy, possibly by exerting an antiproteinuric effect. Aldosterone might have a ...