“Only one of the two cells is truly totipotent, meaning it can give rise to body and placenta, and the second cell gives rise mainly to placenta.” The findings help elucidate what happens during the ...

It is allowing people to do biochemistry with mammalian embryos that they couldn’t do otherwise. After a sperm fertilizes an egg, the totipotent cell divides into a zygote. As division continues, some ...

Stem cells can be unipotent, multipotent, pluripotent or totipotent, depending on the number of cell types to which they can give rise. In individuals receiving an allogeneic haematopoietic cell ...

At this point, each of the eight cells is identical and totipotent, capable of developing into both the embryo and placenta.

then the early embryo undergoes profound changes in its genomic architecture and reprograms the chromatin from a germ cell to a totipotent state. During the maternal-to-zygotic transition in ...

The germ cell lineage ensures the creation of new individuals, diversifying the genetic and epigenetic information. We have succeeded in inducing mouse embryonic stem cells (mESCs)/induced pluripotent ...