Troponin is shown in red (subunits not distinguished). Upon binding calcium, troponin moves tropomyosin away from the myosin-binding sites on actin (bottom), effectively unblocking it. Modified ...

Her research is focused on the mechanism of sarcomere proteins in heart muscle contraction. She aims to understand how troponin, specifically troponin I (TnI), contributes to the dynamic thin filament ...

Cell motility, regulation of cell shape and the mechanism and regulation of muscle contraction ... and tropomyosin’s ability to regulate muscle contraction via the calcium/troponin system. We are also ...