For patients with polycystic kidney disease (PKD), a common genetic disorder that ravages the waste-removing organ with cysts ...

The targeting of transport vesicles to the correct membrane destination involves a much larger set of proteins than anticipated and several layers of protein–protein interactions. The process of ...

For patients with polycystic kidney disease (PKD), a common genetic disorder that ravages the waste-removing organ with cysts ...

Recent imaging studies reveal that these vesicles are primarily internalized by target cells through clathrin-independent endocytosis, involving proteins galectin-3 and LAMP-2C, rather than fusion.

This graphic illustrates paracrine adhesion signaling on small extracellular vesicles, which secretes a protein called galectin-3, which promotes endocytosis so the vesicle can be absorbed into ...

An interdisciplinary team led by Prof. Yao Zhongping, Associate Head and Professor of the Department of Applied Biology and ...

A study from Rutgers University presents a new method for tracking polycystin proteins in polycystic kidney disease (PKD).

The following is a summary of "Proteomic profiling and functional analysis of extracellular vesicles from ...

By influencing calcium homeostasis, local protein synthesis and the endoplasmic reticulum, a small protein called Rab10 emerges as a crucial cytoplasmic regulator of neuropeptide secretion.