NFL Week 5 betting spreads, lines, point totals for every game on the Week 5 NFL schedule, with odds for favorites and underdogs in each NFL matchup.

Week 5 of the NFL season is the first week in which not every team will play. Four teams will be on their bye, meaning there will only be 14 games on the schedule. This week, there will be a Thursday night game,

Some teams have solidified their status as contenders. Others need to begin turning the tides in Week 5. In 2023, the Browns were 2-2 going into Week 5 before winning five of its next six games and later advancing to the postseason. There’s a chance we see a similar emergence from a darkhorse contender.