After taking The Substance, a younger version of Elisabeth named Sue (played by Margaret Qualley) emerges from a cut in her back. As Elisabeth lays unconscious, Sue ventures out into the world where ...

The Substance, which stars Demi Moore, Margaret Qualley, and Dennis Quaid, centers around the idea of self-transformation, youth, and body image as an aerobics celebrity (Moore) hits the milestone of ...

Coralie Fargeat’s bold, bloody and buzzy “The Substance” has become the most successful box office release for arthouse ...

"The Substance" tells the story of actress Elizabeth Sparkle's desperate measures to remain young and relevant on the ...

The Substance, starring Demi Moore and Margaret Qualley, hits its first global box office milestone in its opening weekend.

New research shows that lower sustained attention in adolescence can predict a higher likelihood of cigarette and cannabis ...

A San Antonio man is undertaking an ambitious cross-country run to raise money and awareness for families struggling with ...

After investigating a suspicious package that was mailed to the Secretary of State's Office on Friday, officials have ...

For much of the 1990s, Demi Moore was one of "the biggest female box-office draws in Hollywood", said Alistair Harkness in ...

The scene draws viewers into the universe of The Substance, the new body horror film starring Demi Moore and Margaret Qualley ...

If you have five or so hours to spare and a reasonably strong stomach, I’d recommend a double bill of The Substance and A Different Man. They’re both boldly conceived, darkly funny cautionary tales ...