They found that in UC patients, the lower levels of 7α-dehydroxylated bile acids strongly correlated with impaired intestinal cell renewal. This reinforces the link between bile acid metabolism ...

Lithocholic acid (LCA) is a hepatotoxic compound. Fetal LCA might play a role in the pathogenesis of neonatal cholestasis/EHBA. Recent results show that fetal liver has capacity for hydroxylations ...

EPFL researchers discover that Clostridium scindens can restore bile acid balance, aiding gut healing and offering a ...

The human gut is home to trillions of bacteria that play vital roles in digestion, immunity, and overall health. When this microbial balance is disturbed, it can contribute to the development of ...

Drug-induced liver injury (DILI) is a significant concern in clinical practice, arising from medications, herbs, and dietary ...

The human gut is home to trillions of bacteria that play vital roles in digestion, immunity, and overall health. Disruption of the interaction between the gut microbiome and the host can ...

A new study published in the journal Liver International sheds light on changes to the fetus's bile acid, which affects how liver disease develops and progresses.

When they tested the therapy in mice lacking this receptor, the benefits disappeared, confirming that bile acid metabolism is essential for healing.