In chronic low back pain, botulinum neurotoxin type A improved patients' pain and functional outcomes vs placebo and other local injection therapies.

More information: Basavraj Khanppnavar et al, Cryo-EM structure of the botulinum neurotoxin A/SV2B complex and its implications for translocation, Nature Communications (2025). DOI: 10.1038/s41467 ...

Botox has been a widely used neurotoxin for years, while Daxxify was more recently approved by the Food and Drug Administration (FDA) in 2022. Both drugs are derivatives of botulinum neurotoxin ...

Clostridium botulinum produces potent neurotoxins that block neurotransmitter release at femtomolar concentrations, and cause the neuroparalytic syndrome of botulism. So far, molecular details of ...

Foodborne botulism, caused by botulinum neurotoxin-producing clostridia, is a severe and potentially fatal disease resulting from the ingestion of pre-formed toxin in foods that are improperly ...

One form of treatment paused in the UK during the early days of the pandemic was botulinum neurotoxin (BoNT) injections, and as a result some patients have gone months without treatment.

Your doctor may prescribe different medications to treat MS. But in addition to those meds, they may also order botulinum neurotoxin (Botox) for MS to treat spasticity. Each of the above ...

Identification of Biological Targets to Reduce Muscle Stiffness and Optimize Function Following Long-Term Botulinum Neurotoxin Therapy in Cerebral Palsy. Cerebral Palsy (CP) is the most common cause ...

and genetic regulation of botulinum neurotoxin production and spore formation, stress and adaptive mechanisms, and ecology and cultural dynamics Applied research questions focus on diagnostics and ...