Infected bug bites may require a course of antibiotics. Seek urgent medical treatment if you develop red skin streaks, the bite area spreads, your pain worsens, or you develop symptoms of sepsis.

Insect and spider bites can cause small lacerations, swelling, skin discoloration, blisters, and other symptoms. Home treatment may relieve symptoms but some bites may need medical attention.

If the symptoms do not improve in 5 to 15 minutes, or they come back, use a second pen if the ... allergic reactions to insect bites, and hives — can cause a similar rash. A person should ...