In 1500 Cesare married Charlotte d’Albret ... She seemed to rise above the misfortune into which the rest of the Borgia family were falling. Pope Alexander VI died a year later, in August ...

In the early 16th century Italy is ruled by the powerful Borgia family, led by Cesare Borgia and his sister Lucrezia. In a ruthless power play, Cesare plots to have his sister’s husband murdered.