A global research collaboration has revealed how certain gut cells switch on pain signals, which can linger long after the ...
More information: Nick J. Spencer et al, Identification of vagal afferent nerve endings in the mouse colon and their spatial relationship with enterochromaffin cells, Cell and Tissue Research (2024).
But the serotonin was not coming from the enterochromaffin cells, the cells that produce serotonin in adults, but rather from the gut’s resident bacteria. When they isolated bacteria from both ...
Serotonergic enterochromaffin cells of the intestine exhibit distinct sensory, secretory and physiological properties depending on their location within the complex crypt–villus architecture of ...
Circulating serotonin is produced in the duodenum by enterochromaffin cells, specialized endocrine cells in the epithelia lining the gut, and functions within a specialized neuroendocrine network.