Hepatocellular carcinoma Fatty acid synthase Cholesterol biosynthesis HMG-CoA reductase ... resulting in the increased expression of genes involved in cholesterol biosynthesis. When analysing the ...

Bile-acid-binding resins are therefore primarily used to manage hypercholesterolaemia, but the significant lipid loss they induce, including loss of fatty acids, may perhaps lead to a more general ...

Homeostasis is the result of variables being regulated such that the internal environment remains stable and fairly constant even though the external environment varies. For example, in humans ...

Retinoic acid-inducible gene I (RIG-I) is a cytosolic pattern recognition receptor that contains two CARD domains, an RNA helicase domain, and a C-terminal domain. RIG-I initiates antiviral innate ...

New 1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-2-phenylisoquinoline-1(2H)-ones as Phosphoinositide 3-kinase Inhibitors for Treating Cancer and other Diseases.

Phytoestrogen compounds and bacterial metabolites can also stimulate epigenetic changes in the brain, resulting in potential disruptive gene expression changes ... of metabolites associated with ...