Recent research has focused on understanding the complex systems involved in heme biosynthesis and the maturation ... bacterial and eukaryotic maturation pathways. For example, the eukaryotic ...

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

Stock analysts at Leerink Partnrs boosted their FY2025 earnings estimates for shares of Disc Medicine in a report issued on Wednesday, February 5th. Leerink Partnrs analyst T. Smith now anticipates ...

X-linked sideroblastic anemia (XLSA) is a rare genetic disorder caused by mutations in the ALAS2 gene, which plays a critical role in heme biosynthesis within red blood cells. Lentiviral vector ...

We are building a portfolio of innovative, potentially first-in-class therapeutic candidates that aim to address a wide spectrum of hematologic diseases by targeting fundamental biological pathways of ...

The Wood–Ljungdahl pathway for acetogenesis is a key early biosynthetic pathway with the potential to ... Genes involved in export of lipooligosaccharides, heme (used in membrane-bound succinate ...

Besides their metabolic role, these enzymes are involved in plant signaling pathways as this reaction is in several ... To attain oxygen activation, most dioxygenases use a non-heme iron cofactor ...

Researchers have revealed how Staphylococcus aureus bacteria extract iron from hemoglobin—a process crucial to their survival ...

WATERTOWN, Mass., Jan. 21, 2025 (GLOBE NEWSWIRE) -- Disc Medicine, Inc. (NASDAQ:IRON), a clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of novel ...

In 2025, Canada will unveil four new permanent residency pathways aimed at tackling labor shortages and creating more opportunities for foreign nationals. These initiatives include the Enhanced ...

Overall, digital pathways in education and skills development can be seen as the interplay of two dimensions: (1) depth of digital transitions, the extent to which public policy efforts take a ...