Chronic rhinosinusitis with nasal polyps presents a substantial clinical ... Epithelial barrier dysfunction and type 2 inflammatory responses drive disease progression. Treatments such as ...

uncontrolled asthma and coexisting chronic rhinosinusitis with nasal polyps and suggest that the reduction in multiple downstream inflammatory signaling may modify disease severity in the patients ...

Not only adults, nasal polyps can also occur in children. Polyps are an inflammation of the nasal membranes and sinuses that lasts more than 12 weeks. This condition is actually a soft, painless, ...

Nasal polyp and congestion scores fell ... By acting at the top of the inflammatory cascade, he said, tezepelumab is critical in the initiation and persistence of multiple downstream inflammatory ...

which said it remains committed to brining the drug to patients with the inflammatory condition, which results in the growth of nasal polyps in the nose that can sometimes require surgical ...

CRSwNP is an inflammatory condition which results in the growth of nasal polyps in the nose that can sometimes require surgical intervention. Around 40% of cases are uncontrolled and – in severe ...

March 12, 2025 (GLOBE NEWSWIRE) -- Upstream Bio, Inc. (Nasdaq: UPB), a clinical-stage company developing treatments for inflammatory ... rhinosinusitis with nasal polyps (CRSwNP), severe asthma ...

A new CT-scan-based risk score facilitates the identification of patients at risk of revision endoscopic sinus surgery due to ...

Excessive bacterial colonization in the nasal cavity can result in nasal polyp formation ... to maximize therapeutic benefits while avoiding inflammatory responses. Hormone-secreting engineered ...

Upstream Bio’s (NASDAQ:UPB – Get Free Report) lock-up period will end on Wednesday, April 9th. Upstream Bio had issued 15,000,000 shares in its initial public offering on October 11th. The total size ...