Pelareorep plus chemotherapy with or without Tecentriq had an acceptable safety profile in patients with newly diagnosed ...

The Phase 1/2 GOBLET study is testing pelareorep, an oncolytic reovirus, in combination with other treatments for advanced gastrointestinal cancers, including pancreatic, colorectal, and anal cancers.

Figure 2: Inhibition of caspase 3, apoptosis (caspase 3 activation) and survival in reovirus-infected mice. Apoptotic cells occur in the CNS, heart and liver following infection with various ...

Oncolytic viruses (OVs) are viruses that infect and kill cancer cells while sparing healthy tissue, making them a promising therapeutic option in cancer ...

Detailed price information for Zentalis Pharmaceuticals Inc (ZNTL-Q) from The Globe and Mail including charting and trades.

Following a positive safety review by the independent Data Safety Monitoring Board (DSMB), which recommended continuation, the PEI's approval allows Cohort 5 to progress to full enrollment. Early ...

Detailed price information for Oncolytics Biotech Inc (ONCY-Q) from The Globe and Mail including charting and trades.

Avian Reovirus (ARV) is a significant viral pathogen that is extensively prevalent in poultry, leading to respiratory, gastrointestinal, and joint diseases (Ayalew et al., 2017). For instance, several ...

Although only a small subset of patients with metastatic PDAC who have microsatellite instability–high or mismatch repair–deficient tumors experience efficacy with immunotherapy, previous data have ...