ASCO Guidelines provide recommendations with comprehensive review and analyses of the relevant literature for each recommendation, following the guideline development process as outlined in the ASCO ...

Department of Anatomy and Neurobiology, College of Medicine, Kyung Hee University, Seoul 02447, Republic of Korea Department of Precision Medicine, Graduate School, Kyung Hee University, Seoul 02447, ...

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SARS-CoV-2 is able to infect human cells by binding its spike (S) protein to angiotensin-conversing enzyme 2 (ACE2), which is expressed abundantly in several cell types and tissues. ACE2 has extensive ...

Neoantigens, specific to cancer cells and absent in normal tissues, are at the heart of these vaccines, promising to direct the immune system specifically against the tumor, thereby maximizing ...

This useful study by Gao et al identifies Hspa2 as a heterogeneous transcript in the early embryo and proposes a plausible mechanism showing interactions with Carm1. The authors propose that ...

Capillary-based immunoassays were performed using the Wes-Simple Western method (Proteintech: HSPA2 (12797-1-AP), 1:15 dilution; GAPDH (10494-1-AP),1:35 dilution; SOX2 (11064-1-AP), 1:20 dilution; ...

The favourable toxicity profile in animals and its administration as a simple intravenous injection has motivated ... survival without increasing the dose in the surrounding healthy tissues.

Major Finding: A cancer-associated fibroblast (CAF)–epithelial cell niche shields squamous cell carcinomas (SCC) from antitumor immune responses. Concept: Epithelial JAG1–NOTCH1 signaling promotes the ...