His research aims to identify the role of extracellular vesicles from intestinal epithelial cells (IEC-EVs) in the development of acute graft-versus-host disease (aGvHD) following allogeneic stem ...

This important study shows that the Nora virus, a natural Drosophila pathogen that also persistently infects many laboratory fly stocks, infects intestinal stem cells (ISCs), leading to a shorter life ...

Researchers have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer. A professor of pediatrics-developmental biology and an assistant professor of ...

Knocking out a single gene reprograms part of the large intestine to function like the nutrient-absorbing small intestine. In a preclinical study ...

Most of the time, the intestinal immune system can recognize friend from foe, tolerating myriad foods while destroying ...

The intestine has an enormous ability to regenerate itself after injury, and it does this through a model of dedifferentiation. The cells dedifferentiate back into a type of regenerative stem cell ...

Most of the time, the intestinal immune ... to the immune system's T cells, instructing those cells to remain unresponsive to the harmless intruder. More recently, a small population of cells ...

This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...

Researchers from the University of Colorado Cancer Center have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer. Peter Dempsey, PhD, professor of ...