Would Trey Sermon, Tyler Goodson or a committee replace Jonathan Taylor? Who is Jonathan Taylor's backup on the Colts depth chart? Trey Serm

The Indianapolis Colts are preparing to be without star running back Jonathan Taylor as he deals with a high-ankle sprain. After being awkwardly tackled during the fourth quarter of the Week 4 win over the Pittsburgh Steelers, Taylor was diagnosed with a mild high-ankle sprain.

We’re officially through four weeks of the NFL season, and the injuries continue to pile up. Colts quarterback Anthony Richardson left his team's game against the Steelers with an oblique strain. His teammate Jonathan Taylor exited earlier with an ankle injury. Packers receiver Christian Watson also suffered a high ankle sprain against the Vikings.