Proteasome activator 28γ (PA28γ) plays a critical role in malignant progression of various tumors, however, its role and regulation are not well understood. Here, using oral squamous cell carcinoma ...

Researchers have identified a set of geological reaction conditions that may have catalysed life on Earth. Researchers have discovered a plausible evolutionary setting in which nucleic acids – the ...

This useful study by Gao et al identifies Hspa2 as a heterogeneous transcript in the early embryo and proposes a plausible mechanism showing interactions with Carm1. The authors propose that ...

Changes in neural activity thought to reflect brain aging may be partly influenced by age-dependent signals ‘leaking’ from the heart.

This important work shows how a simple geophysical setting of gas flow over a narrow channel of water can create a physical environment that leads to the isothermal replication of nucleic acids. The ...

In sum, odors initiate feeding behavior in Drosophila.

Tissue necrosis is a devastating complication for many human diseases and injuries. Unfortunately, our understanding of necrosis and how it impacts surrounding healthy tissue – an essential ...

Here we derive a general empirically-grounded theory that can explain this phenomenon by linking microbial species richness in competitive communities to variation in the temperature-dependence of ...