How the gut triggers lasting pain in common conditions
A global research collaboration has revealed how certain gut cells switch on pain signals, which can linger long after the ...
The Scientist3mon
Gut Serotonin Curbs the Developing Immune System
But the serotonin was not coming from the enterochromaffin cells, the cells that produce serotonin in adults, but rather from the gut’s resident bacteria. When they isolated bacteria from both ...
Nature11y
Overexpression of gastric leptin precedes adipocyte leptin during high-fat diet and is linked to 5HT-containing enterochromaffin cells
Enterochromaffin (EC) cells and expression of leptin, PAX4 (critical factor for EC specification), tryptophane hydroxylase-1 (TPH1, the peripheral rate-limiting enzyme for 5HT) and 5HT were ...
Nature7d
Somatosensory system articles from across Nature Portfolio
Serotonergic enterochromaffin cells of the intestine exhibit distinct sensory, secretory and physiological properties depending on their location within the complex crypt–villus architecture of ...