Investigators hypothesized that this virus is lethal because it induces an unusually potent proinflammatory cytokine response ... other human influenza viruses (H1N1 and h4N2) and used cDNA ...

Diseases such as covid-19 and influenza can be fatal due to an overreaction of the body’s immune system called a cytokine storm. Cytokines are small proteins released by many different cells in ...

Unexpected findings now identify multiple secreted inflammatory cytokines, their cognate receptors and positive-feedback loops with corresponding transcription factors, as key mediators of both ...