The kidneys are responsible for keeping the creatinine level in the blood within a normal range. Medical professionals define the typical reference ranges for serum creatinine in micromoles per ...

Normal stools can vary in shades of brown ... If the cause is liver disease or a blocked bile duct, this can be life threatening and may require surgery or medications. An experienced healthcare ...

The investigators initially enrolled all comers with advanced or metastatic cancers likely to express CLDN18.2, such as gastric, pancreatic, or esophageal tumors, and tested patients' tumors for ...

What Is Metastatic Bile Duct Cancer and Its Causes? Bile duct cancer – also called cholangiocarcinoma – is a rare condition. When you have cholangiocarcinoma, cancer cells grow in your bile ...

The common bile duct and common hepatic duct are important in this process, making sure the bile flows from the liver to the gallbladder and small intestine. The cystic duct connects the ...

The following is a summary of “Innovative Construction and Application of Bile Duct Organoids: Unraveling the Complexity of Bile Duct Diseases and Potential Therapeutic Strategies,” published in the ...

A study shows that the semi-synthetic bile acid NorUDCA inhibits in the intestine the formation of pro-inflammatory T helper 17 cells (TH17) and at the same time promotes the generation of anti ...

Michelle Black, 50, from Wheathampstead, Hertfordshire, received the joyous news that she had overcome a rare bile duct cancer in November. However, her world was shattered five days before ...

1 Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun, China 2 Cancer Center, The First Hospital of Jilin University, ...

Statistical analyses were executed using R software (version 4.2.0). For data that adhered to a normal distribution, results are reported as mean ± standard deviation, and the independent sample ...

Clostridium scindens acts as a promising biotherapeutic to restore bile acid (BA) homeostasis, which is altered in ulcerative colitis (UC) patients. Its 7α-dehydroxylated BA products alleviate disease ...

NEW YORK – I-Mab said on Friday it has completed enrollment of the dose expansion cohort in a Phase Ib trial of givastomig, a Claudin 18.2 (CLDN18.2) and 4-1BB bispecific antibody, with immunotherapy ...