When exposed to antibiotics, approximately one out of every 10 8 -10 9 bacteria develops resistance due to spontaneous ...

Inhibitors of Apoptosis Proteins (IAPs) are a family of anti-apoptotic proteins that play a pivotal role in apoptosis in general but also as oncoproteins in cancer progression and, more importantly, ...

Transcription factors are proteins ... "The inhibitor works a bit like a harpoon that fires across to the target and won't let go—it grips the cJun tightly and stops it from binding to the ...

SARS-CoV-2, the virus responsible for COVID-19, infects cells by binding its spike protein to angiotensin-converting enzyme 2 (ACE2) receptors. Blocking this interaction with inhibitors could ...

LEN is a first-in-class, long-acting HIV-1 capsid inhibitor that disrupts multiple stages of the viral replication cycle. By binding to the capsid protein, it blocks the nuclear import of HIV-1 ...

In rod-shaped Escherichia coli, two conserved sets of machinery are essential for cell-wall insertion in the cylindrical part of the cell: the Rod complex and the class-A penicillin-binding proteins .

Seeding, in the context of amyloid disease, is the sequential transfer of pathogenic protein ... inhibitors based on the atomic structure of the core of α-syn fibrils. The inhibitors prevent α-syn ...