At least 16 people were killed in weather-related fatalities this week, including tornadoes that destroyed entire neighborhoods.

The National Weather Service says a "multi-day catastrophic and potentially historic" storm is expected to impact multiple states. Thousands have lost power in Missouri and other states, and a person was killed Wednesday evening in the southeast part of the state.

Northeastern Arkansas saw a tornado emergency issued as a large twister hit Lake City. The tornado was a part of a storm sweeping from Texas to Ohio.