Osteopetrosis ("marble bone disease") is a descriptive term that refers to a group of rare, heritable disorders of the skeleton characterized by increased bone density on radiographs. The overall …

Autosomal recessive osteopetrosis (ARO), also known as malignant infantile osteopetrosis or infantile malignant osteopetrosis (IMO), is a rare type of skeletal dysplasia characterized by a …

Feb 20, 2009 · Osteopetrosis ("marble bone disease") is a descriptive term that refers to a group of rare, heritable disorders of the skeleton characterized by increased bone density on …

Oct 2, 2015 · Introduction: Osteopetrosis, a rare disorder due to osteoclast dysfunction, which causes bone resorption dysfunction. These patients have brittle bones prone to osteomyelitis.

The name osteopetrosis is derived from the Greek language. ‘Osteo’ means bone, and ‘petrosis,’ meaning stone. Therefore, the disease is often referred to colloquially as “marble bone …

Feb 20, 2009 · Osteopetrosis ("marble bone disease") is a descriptive term that refers to a group of rare, heritable disorders of the skeleton characterized by increased bone density on …

Although osteoclast dysfunction results in high bone mineral density, the affected bones are unusually brittle. There are four forms of osteopetrosis, including the malignant autosomal …

Osteopetrosis intermediate type can be inherited as an autosomal recessive or autosomal dominant genetic trait. People with specific questions about genetic risks or genetic testing for …

The autosomal dominant adult (benign) form is associated with few, if any, symptoms, and the autosomal recessive infantile (malignant) form is typically fatal during infancy or early …

Oct 2, 2015 · Osteopetrosis, or marble bone disease, is a rare skeletal disorder due to a defective function of the osteoclasts. This defect renders bones more susceptible to osteomyelitis due to …