Mar 30, 2025 · LIPE (Lipase E, Hormone Sensitive Type) is a Protein Coding gene. Diseases associated with LIPE include Lipodystrophy, Familial Partial, Type 6 and Mandibular …

Lipophilic efficiency [1] (LiPE), sometimes referred to as ligand-lipophilicity efficiency (LLE) is a parameter used in drug design and drug discovery to evaluate the quality of research …

Koh Lipe island offers pristine white beaches, palm tree forests and crystal clear waters for amazing snorkeling. Find everything you need to know about Koh Lipe right here!

Those findings indicate improvement and conservation of lifestyle depending on genetic predisposition in ADIPOQ, PLIN and LIPE should be encouraged. The present study aimed at …

Lipophilic efficiency (LipE), also referred to as ligand-lipophilicity efficiency (LLE) represents the relationship between the target binding of interest (measured as IC 50 or EC 50) and the …

Jun 26, 2024 · Lipophilic efficiency (LipE) and lipophilic metabolic efficiency (LipMetE) are valuable tools that can be utilized as part of a multiparameter optimization process to advance …

LIPE is rapidly activated by cAMP-dependent phosphorylation under the influence of catecholamines. Dephosphorylation and inactivation via protein phosphatases or inhibition of …

Aug 9, 2018 · Lipophilic efficiency (LipE) is an important metric that has been increasingly applied in drug discovery medicinal chemistry lead optimization programs.

Hormone-sensitive lipase (EC 3.1.1.79, HSL), also previously known as cholesteryl ester hydrolase (CEH), [5] sometimes referred to as triacylglycerol lipase, is an enzyme that, in …

Lipophilic efficiency (LipE) is a feature that is used in drug discovery and development that combines drug affinity and lipophilic-driven binding as a method to characterize binding …